MERS-CoV-IN-4

Overview

MERS-CoV-IN-4 is an orally active antiviral inhibitor targeting the MERS-CoV spike (S) protein, with an IC 50 of 0.009 μM in Huh-7 cells, and K d values of 7.72 μM for the full-length S protein and 5.09 μM for S-RBD. MERS-CoV-IN-4 inhibits viral entry, and suppresses MERS-CoV pseudoviruses and live viruses in vitro. MERS-CoV-IN-4 reduces pulmonary viral loads in hDPP4 transgenic mice. MERS-CoV-IN-4 can be used for research on Middle East respiratory syndrome coronavirus infection .

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Coronavirus Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > SARS-CoV

Product Information

• Catalog No.: HY-184669
• CAS No.: 2740494-38-4
• Molecular Formula: C19H22N4S
• Molecular Weight: 338.47
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source