Morfamquat dichloride (PP 745) is a bipyridine herbicide . Acute poisoning by Morfamquat dichloride strongly stimulates the reticuloendothelial system, causes lysosomal membrane damage and enzyme leakage, and interferes with the function of hepatocyte Golgi apparatus and related glucose metabolic pathways. Morfamquat dichloride significantly increases the activities of acid phosphatase and β-glucuronidase , exerting toxic effects on mice, while pre-administration of vitamin E alleviates such toxicity.
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