Mal-Val-Lys-PAB-CBI-PBD dimer

Overview

Mal-Val-Lys-PAB-CBI-PBD dimer is a Drug-Linker Conjugates for ADC . Mal-Val-Lys-PAB-CBI-PBD dimer consists of the ADC Cytotoxin CBI-PBD dimer and a linker Mal-Val-Lys-PAB. Mal-Val-Lys-PAB-CBI-PBD dimer exhibits alkylating activity at A-T-rich DNA minor groove adenine residues, disrupting DNA integrity. Mal-Val-Lys-PAB-CBI-PBD dimer induces cancer cell growth inhibition and cellular death. Mal-Val-Lys-PAB-CBI-PBD dimer can be used for the research of cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Drug-Linker Conjugates for ADC | Products > Signaling Pathways > DNA Alkylator/Crosslinker

Product Information

• Catalog No.: HY-185494
• CAS No.: 1661824-39-0
• Molecular Formula: C67H85ClN10O14
• Molecular Weight: 1289.90
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source