OKI-005 is an orally active inhibitor of Class I HDACs , with primary targeting of HDAC1 , HDAC2 and HDAC3 . OKI-005 is a prodrug of OKI-006 ( HY-144893 ). OKI-005 increases histone acetylation levels, induces apoptosis and inhibits cancer cell proliferation. OKI-005 can be used in research related to triple-negative breast cancer and colorectal cancer .
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