JNJ-27548547

Overview

JNJ-27548547, Mitomycin C (HY-13316) prodrug, is a Mitomycin C and lipophilic group conjugate. JNJ-27548547 undergoes thiolytic cleavage of its dithiobenzyl linker in the presence of reducing agents to release active substance Mitomycin C. JNJ-27548547 is formulated into pegylated liposomes (PL-MLP) with high antitumor activity in mice models.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Others | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Drug Intermediate

Product Information

• Catalog No.: HY-185585
• CAS No.: 303983-00-8
• Molecular Formula: C62H98N4O11S2
• Molecular Weight: 1139.59
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source