SGI-1776-VHL-02-epimer

Overview

SGI-1776-VHL-02 -epimer (SGI-1776-cis-VHL-02) is an epimer control compound of with SGI-1776-VHL-02 ( HY-186146 ). SGI-1776-VHL-02 -epimer has an inverted stereocenter in the critical hydroxyl-proline group in the VHL ligand. SGI-1776-VHL-02 -epimer cannot trigger the VHL E3 ligase complex and does not degrade PIM1 .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Others | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Drug Isomer | Products > Signaling Pathways > Pim | Products > Signaling Pathways > c-Myc

Product Information

• Catalog No.: HY-186146A
• CAS No.: 3013618-85-1
• Molecular Formula: C50H62F3N9O6S
• Molecular Weight: 974.14
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source