TMEM175 agonist 1 is a TMEM175 agonist, with a human EC 50 of 0.378 μM in FLIPR assays and a human EC 50 of 0.886 μM in EP analyses. TMEM175 agonist 1 can be used in the research of Parkinson's disease, dementia with Lewy bodies, rapid eye movement sleep behavior disorder, amyotrophic lateral sclerosis, and lysosomal storage diseases.
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