DPC423 free base

Overview

DPC423 free base is a selective and orally active factor Xa inhibitor with a K i s of 0.15 (human) and 0.3 (rabbit) nM. DPC423 free base exhibits K i s of 60, 61 and 6000 nM against human trypsin , plasma kallikrein and thrombin . DPC423 free base blocks the formation of prothrombinase complex, reduces thrombin production, inhibits fibrin formation and platelet activation. DPC423 free base can be used for the study of anticoagulation of arterial thrombosis.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Factor Xa | Products > Signaling Pathways > Kallikrein | Products > Signaling Pathways > Thrombin | Products > Signaling Pathways > Ser/Thr Protease

Product Information

• Catalog No.: HY-11090
• CAS No.: 209957-47-1
• Molecular Formula: C25H20F4N4O3S
• Molecular Weight: 532.51
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source