DPC423

Overview

DPC423 is a selective and orally active factor Xa inhibitor with a K i s of 0.15 (human) and 0.3 (rabbit) nM. DPC423 exhibits K i s of 60, 61 and 6000 nM against human trypsin , plasma kallikrein and thrombin . DPC423 blocks the formation of prothrombinase complex, reduces thrombin production, inhibits fibrin formation and platelet activation. DPC423 can be used for the study of anticoagulation of arterial thrombosis.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Factor Xa | Products > Signaling Pathways > Kallikrein | Products > Signaling Pathways > Thrombin | Products > Signaling Pathways > Ser/Thr Protease

Product Information

• Catalog No.: HY-11090A
• CAS No.: 292135-59-2
• Molecular Formula: C25H21ClF4N4O3S
• Molecular Weight: 568.97
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source