BP79 is a potent TSLP receptor inhibitor. BP79 disrupts TSLP -mediated ternary complex formation, blocks TSLPR - IL7Rα co-localization, binds and stabilizes TSLPR , and inhibits phosphorylated STAT3/6 . BP79 suppresses immune cell infiltration, secretion of IL-13 , IL-4 . BP79 can be used for the research of inflammation diseases, such as atopic dermatitis, allergic asthma, and allergic rhinitis.
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