D-Captopril

Overview

D-Captopril is a NDM-1 inhibitor and a competitive BlaB inhibitor, with an IC 50 value of 21.8 µM against NDM-1 and a K i of 70-100 µM against BlaB . D-Captopril synergistically reduces the minimum inhibitory concentration of Meropenem ( HY-13678 ) against NDM-1-expressing bacteria. D-Captopril binds to BcII via its thiolate sulfur atom and carboxylate group, altering metal ion occupancy and modulating Cd 2+ binding affinity. D-Captopril can be used in the research of neonatal meningitis, sepsis and bacterial infections.

Application

Products | Products > Disease Areas > Pathogens Infection | Products > Disease Areas > Bacterial Infection | Products > Disease Areas > Meningitis | Products > Disease Areas > Sepsis | Products > Disease Areas > Infection | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > CNS Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Signaling Pathways > Beta-lactamase | Products > Signaling Pathways > Antibiotic | Products > Signaling Pathways > Bacterial

Product Information

• Catalog No.: HY-B0368B
• CAS No.: 119238-52-7
• Molecular Formula: C9H15NO3S
• Molecular Weight: 217.29
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source