Tebipenem pivoxil hydrobromide

Overview

Tebipenem pivoxil hydrobromide (L084 hydrobromide) is an orally active carbapenem Antibiotic . Tebipenem pivoxil hydrobromide acts as a substrate of OATP1A2 with high affinity for this transporter ( K m = 41.1 μM) . Tebipenem pivoxil hydrobromide achieves intestinal absorption via carrier-mediated uptake and simple diffusion. Tebipenem pivoxil hydrobromide inhibits the growth of Gram-positive bacteria, Gram-negative bacteria, multidrug-resistant bacteria, and pathogens producing extended-spectrum β-lactamases. Tebipenem pivoxil hydrobromide eliminates intestinal infection pathogens and reduces mortality in septic mice. Tebipenem pivoxil hydrobromide can be used in research related to bacterial pneumonia, severe gastrointestinal infections, bacterial sepsis, complicated urinary tract infections, and acute pyelonephritis.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Bacterial Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Infection | Products > Signaling Pathways > Antibiotic | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > OAT

Product Information

• Catalog No.: HY-B0396B
• CAS No.: 1381788-20-0
• Molecular Formula: C22H32BrN3O6S2
• Molecular Weight: 578.54
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source