CEMT

Overview

CEMT is a carboxylesterase ( CES ) substrate and a ratiometric two-photon fluorescent reporter probe. CEMT can be hydrolyzed by CES to generate HMT, which is used for mitochondrial pH sensing. After activation by CES, CEMT exhibits ratiometric fluorescence changes in response to pH variations. CEMT targets and covalently binds to mitochondria, and can avoid leakage during acidification, thus enabling in situ imaging (Ex/Em = 410 nm/550 nm).

Application

Products | Products > Disease Areas > Others | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Others | Products > Signaling Pathways > Fluorescent Dye | Products > Signaling Pathways > Carboxylesterase (CES)

Product Information

• Catalog No.: HY-D3166
• CAS No.: 2413816-64-3
• Molecular Formula: C26H21Cl2NO4
• Molecular Weight: 482.36
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source