PiF

Overview

PiF is a fluorescent probe with high specificity for pancreatic β-cells (Ex/Em = 535 nm/565 nm), and its fluorescence signal increases significantly with elevated insulin concentrations in in vitro experiments. PiF enables visualization of rat and human islets transplanted via the portal vein in mouse livers with low liver background signals. The fluorine atom of PiF can be replaced by radioactive 18 F to prepare a PET tracer. PiF can be used for research on type 1 diabetes.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Glucose Metabolism | Products > Disease Areas > Type 1 Diabetes | Products > Signaling Pathways > Others | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Fluorescent Dye

Product Information

• Catalog No.: HY-D3174
• CAS No.: 2688758-23-6
• Molecular Formula: C26H26F4N2O5S
• Molecular Weight: 554.55
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source