NIR‐fluorescent ceramide

Overview

NIR-fluorescent ceramide is a neutral near-infrared ( NIF ) fluorescent probe ( λ em =650 nm) based on the C-bridged nitrobenzoxadiazole SCOTfluor core, which enables visualization of lipid metabolic processes such as sphingolipid trafficking. The emission signal of NIR-fluorescent ceramide increases significantly in liposomal environments. NIR-fluorescent ceramide acts as an intracellular trafficking tracer, localizing to regions surrounding the endoplasmic reticulum and Golgi apparatus within a short period, and then translocating to recycling lysosomes over a longer period, thus enabling real-time visualization of sphingolipid trafficking and biological lipid functions in living cells. NIR-fluorescent ceramide also generates metabolic uptake profiles and provides multiple metabolic readouts in human cancer cell lines.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Fluorescent Dye | Products > Signaling Pathways > Endogenous Metabolite

Product Information

• Catalog No.: HY-D3198
• CAS No.: 2351937-34-1
• Molecular Formula: C33H55N5O5
• Molecular Weight: 601.82
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source