oLOX is a fluorescent activity reporter. oLOX can be activated by lysyl oxidase family ( LOXF ) enzymes , which in turn releases a luciferin fluorescent product that reports LOXF enzyme activity. After oLOX is activated in in vitro fibrotic lung tissues, the fluorescence intensity increases, enabling real-time detection of fibrotic activity. oLOX can be used in studies related to pulmonary fibrosis.
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