MAO Probe 1

Overview

MAO Probe 1 is a reactive two-photon fluorescent probe capable of crossing the blood-brain barrier, which is used to detect the activity of monoamine oxidases ( MAO-A/MAO-B ), with K m values of 70 μM ( MAO-A ) and 75 μM ( MAO-B ), respectively. IBC 2 (benzo[g]imino-coumarin 2), the enzymatic product of MAO Probe 1, can further specifically bind to and image Aβ plaques, enabling in vivo two-photon co-monitoring of MAO activity and Aβ plaques. MAO Probe 1 can be used in Alzheimer's disease research (IBC 2: Ex/Em = 850 nm/570-620 nm).

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Alzheimer's Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Fluorescent Dye | Products > Signaling Pathways > Monoamine Oxidase | Products > Signaling Pathways > Amyloid-β

Product Information

• Catalog No.: HY-D3221
• CAS No.: 1386860-79-2
• Molecular Formula: C19H20N4O
• Molecular Weight: 320.39
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source