16:0-06:0 NBD PE (C6-NBD-PE) is a commonly used fluorescent phospholipid analog and membrane-disrupting agent for investigating membrane lipid structure and dynamics. In aqueous buffers, the self-assembly of 16:0-06:0 NBD PE can be disrupted via binding to methylated α-, β-, and γ-cyclodextrins. 16:0-06:0 NBD PE can be selectively extracted from lipid vesicles upon the addition of methylated cyclodextrins, with an extraction efficiency lower than that of NBD-PC and NBD-SM analogs.
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