Arnicolide B is a sesquiterpene lactone. Arnicolide B is isolated from Centipeda minima . Arnicolide B inhibits the phosphorylation of ERK , JNK and p38 proteins in the MAPK signaling pathway. Arnicolide B reduces the production of inflammatory mediators NO , PGE 2 and IL-6 . Arnicolide B downregulates the overexpression of inflammatory proteins iNOS and COX-2 . Arnicolide B has no effect on IκB-α degradation or NF-κB pathway activation. Arnicolide B is applicable to inflammation-related research.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > COX | Products > Signaling Pathways > p38 MAPK | Products > Signaling Pathways > ERK | Products > Signaling Pathways > JNK | Products > Signaling Pathways > NO Synthase | Products > Signaling Pathways > PGE synthase
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