Isoeucommin A is a lignan compound. Isoeucommin A activates the Nrf2 / HO-1 pathway and induces phosphorylation of GSK-3β . Isoeucommin A reduces the levels of pro-inflammatory cytokines TNF-α , IL-1β and IL-6 , decreases the oxidative stress marker MDA , increases the antioxidants SOD and GSH , and alleviates oxidative stress in mesangial cells. Isoeucommin A alleviates renal tissue injury, improves impaired renal function and enhances the viability of renal tubular epithelial cells in diabetic nephropathy models. Isoeucommin A can be used in the research of diabetic nephropathy.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Autoimmune Disease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > SOD | Products > Signaling Pathways > Keap1-Nrf2 | Products > Signaling Pathways > GSK-3 | Products > Signaling Pathways > TNF Receptor
感谢您来到爆牛贸易,请为我们留言或者使用以下方式联系我们,我们将尽快给您回复,并为您提供最真诚的服务,谢谢。