1-Hydroxy-4αH-1,10-secoeudesma-5(6),10(14),11(13)-trien-12,8β-olide

Overview

1-Hydroxy-4αH-1,10-secoeudesma-5(6),10(14),11(13)-trien-12,8β-olide is a neuroprotective agent. 1-Hydroxy-4αH-1,10-secoeudesma-5(6),10(14),11(13)-trien-12,8β-olide reduces the protein expression levels of iNOS and COX-2 , blocks the DNA-binding activity of NF-κB , and inhibits nitric oxide production. 1-Hydroxy-4αH-1,10-secoeudesma-5(6),10(14),11(13)-trien-12,8β-olide promotes the polarization of microglia to the M2 phenotype by inducing the production of Arg-1 , and alleviates cell damage induced by H 2 O 2 and 6-Hydroxydopamine ( HY-B1081 ).

Application

Products | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > NO Synthase | Products > Signaling Pathways > COX | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Arginase

Product Information

• Catalog No.: HY-N20682
• CAS No.: 2866266-56-8
• Molecular Formula: C15H20O3
• Molecular Weight: 248.32
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source