Bruceoside B is a PI3K/Akt/NF-κB inhibitor . Bruceoside B reduces LPS ( HY-D1056 )-induced nitric oxide release and the secretion of TNF-α, IL-6 and IL-1β, and decreases the activation level of apoptosis . Bruceoside B inhibits the replication, coat protein accumulation and local lesion formation of tobacco mosaic virus ( TMV ), and enhances the anti-infection ability of plants . Bruceoside B can be used in studies related to acute lung injury and tobacco mosaic virus infection .
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