VHPKQHR

Overview

VHPKQHR is a peptide-based delivery enhancer that binds to VCAM-1 . VHPKQHR enables intracellular internalization of relevant nanomaterials and facilitates the targeted delivery of miRNA inhibitors to inflamed endothelial cells and endothelial cells activated by disturbed flow. When conjugated with magnetic mesoporous silica nanoparticles, VHPKQHR achieves targeted accumulation at atherosclerotic plaque sites. When displayed on the surface of polyelectrolyte complex micelles, VHPKQHR enhances the relevant effects of anti-miR-92a in Apoe -/- mice. When conjugated with ultrasmall superparamagnetic iron oxide nanoparticles, VHPKQHR forms a contrast agent for T 1 -weighted magnetic resonance imaging. VHPKQHR can be used in research related to atherosclerosis, stenosis and rheumatoid arthritis.

Application

Products | Products > Disease Areas > Arthritis | Products > Disease Areas > Atherosclerosis and Inflammation | Products > Disease Areas > Rheumatoid Arthritis | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Musculoskeletal and Skin Disease | Products > Disease Areas > Chronic Disease and Inflammation | Products > Disease Areas > Autoimmune Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Transmembrane Glycoprotein | Products > Signaling Pathways > Radionuclide-Drug Conjugates (RDCs)

Product Information

• Catalog No.: HY-P11887
• CAS No.: 1174559-81-9
• Molecular Formula: C39H64N16O9
• Molecular Weight: 901.03
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source