2-(tert-Butyl)-4,6-dimethylphenol

Overview

2-(tert-Butyl)-4,6-dimethylphenol (6-tert-Butyl-2,4-xylenol) is an electrophilic alkylating agent, gasoline antioxidant and hydration substrate. 2-(tert-Butyl)-4,6-dimethylphenol inhibits SERCA activity in rabbit hindleg microsomes with an IC 50 of 53 μM. Oxidation of 2-(tert-Butyl)-4,6-dimethylphenol generates the intermediate BDMP-QM, which covalently modifies nitrogen sites of proteins, polypeptides and free amino acids via Michael addition, triggering covalent modification of macromolecules and mediating cytotoxicity. 2-(tert-Butyl)-4,6-dimethylphenol is widely used in toxicological and biochemical studies of alkylphenols.

Application

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Product Information

• Catalog No.: HY-W016589
• CAS No.: 1879-09-0
• Molecular Formula: C12H18O
• Molecular Weight: 178.27
• Storage: RT, stored under nitrogen. In solvent -80°C, 1 year , -20°C, 6 months
• Availability: In-stock

Source

Original product source