D-Cysteic acid is a competitive inhibitor of the aspartate:alanine antiporter ( AspT ) from Tetragenococcus halophilus . For L-aspartate self-exchange, D-Cysteic acid has a K i of 0.14 mM and an IC 50 of 0.19 mM; for L-alanine self-exchange, it has a K i of 5.0 mM and an IC 50 of 9.0 mM . D-Cysteic acid occupies a distinct substrate-binding site within the substrate transport pathway of AspT, preventing the binding of natural substrates to the transporter . D-Cysteic acid can be used in studies related to substrate recognition and transport mechanisms of transporters.
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