C14-O2 (solution in ethanol)

Overview

C14-O2 is an ionizable cationic lipid (apparent pKa = 6.6) employed in the formulation of lipid nanoparticles (LNPs) for mRNA delivery both in vitro and in vivo. LNPs formulated with C14-O2 and encapsulating mRNA encoding a chimeric antigen receptor (CAR) effectively induce CAR expression and result in B cell aplasia in mice.

Application

PEGylation of Protein, Peptide & Oligo > Lipid Molecules > Ionizable Lipid | PEGylation of Protein, Peptide & Oligo > Lipid Molecules > Branched Lipid | Drug Delivery, Surface Modification > Lipid Molecules > Ionizable Lipid | Drug Delivery, Surface Modification > Lipid Molecules > Branched Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid > Multi chargeable lipid | Products > Lipids In Drug Delivery > Branched Lipid > Branched Lipid

Product Information

• Catalog No.: BP-42671
• CAS No.: 2639634-77-6
• Molecular Formula: C88H181N5O9
• Molecular Weight: 1453.5
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source