K-14585

Overview

K-14585 is a peptide competitive PAR2 antagonist. K-14585 inhibits PAR2-dependent IL-8 production, NF-κB phosphorylation, and p38 signaling. K-14585 reduces SLIGKV ( PAR2 agonist peptide)-induced Ca 2+ mobilisation in primary human keratinocytes.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Protease Activated Receptor (PAR) | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > p38 MAPK

Product Information

• Catalog No.: HY-111214
• CAS No.: 880546-17-8
• Molecular Formula: C51H56Cl2N8O4
• Molecular Weight: 915.95
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source