2-Chloro-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)acetamide

Overview

2-Chloro-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)acetamide is a thalidomide analogue. Thalidomide recruits E3 Ligase for the ubiquitinylation and subsequent destruction of a given protein. This structure features a chloroacetamide, which is a thiol-specific reactive group.

Application

PROTAC > PROTAC Linkers > PROTAC Linkers | Products > PROTAC, Molecular glue > PROTAC Linkers | Products > PROTAC, Molecular glue > PROTAC Linkers > Pomalidomide-amido-chloride | Products > PROTAC, Molecular glue > PROTAC Linkers > Pomalidomide-amido-chloride

Product Information

• Catalog No.: BP-40561
• CAS No.: 1957235-51-6
• Molecular Formula: C15H12ClN3O5
• Molecular Weight: 349.7
• Storage: -20°C
• Availability: In Stock

Source

Original product source