SJ988497

Overview

SJ988497 is a PROTAC molecule designed to degrade JAK2, effectively inhibiting cell proliferation in CRLF2-rearranged cell lines. It also promotes the degradation of the CRBN neosubstrate GSPT1. Structurally, it includes a Ruxolitinib derivative, a linker, and a CRBN ligand (Pomalidomide), making it useful for studying protein degradation mechanisms. Reagent-grade; for laboratory research purposes only.

Application

Products > PROTAC, Molecular glue > Degraders

Product Information

• Catalog No.: BP-42175
• CAS No.: 2595365-41-4
• Molecular Formula: C36H36N10O5
• Molecular Weight: 688.8
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source