JNJ-26070109

Overview

JNJ-26070109 is a high-affinity, competitive, orally bioactive, and selective cholecystokinin 2 ( CCK2 ) receptor antagonist with good pharmacokinetic properties, with pK i s of 8.49, 7.99, and 7.70 for human, rat, and dog CCK2 receptors, respectively. The dual function of CCK2 receptors in regulating gastric acid secretion and growth of the gastrointestinal mucosa make this an attractive and novel target for the research of gastroesophageal reflux disease.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Cholecystokinin Receptor

Product Information

• Catalog No.: HY-111313
• CAS No.: 844645-08-5
• Molecular Formula: C23H17BrF2N4O3S
• Molecular Weight: 547.37
• Purity: 99.25%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (9.13 mM); Clear solution
• Availability: In-stock

Source

Original product source