Thalidomide-O-C5-azide

Overview

Thalidomide-O-C5-azide is a click chemistry modification of the cereblon (CRBN) inhibitor Thalidomide (HY-14658). Thalidomide-O-C5-azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. Thalidomide-O-C5-azide can be used as a ligand of E3 ubiquitin ligase and Linker conjugates (E3 Ligase Ligand-Linker Conjugates) for the synthesis of PROTACs.

Application

PROTAC > PROTAC Linkers > PROTAC Linkers | Products > PROTAC, Molecular glue > PROTAC Linkers | Products > PROTAC, Molecular glue > PROTAC Linkers > Thalidomide-O-Azide | Products > PROTAC, Molecular glue > PROTAC Linkers > Thalidomide-O-Azide

Product Information

• Catalog No.: BP-44763
• CAS No.: 2411098-96-7
• Molecular Formula: C18H19N5O5
• Molecular Weight: 385.4
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source