CbzNH-PEG4-CH2COOH

Overview

CbzNH-PEG4-CH2COOH is a PEG linker containing an carboxylic acid (CO2H) group and a benzyl (Cbz) protecting group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The terminal carboxylic acid is reactive with primary amine groups in the presence of activators (e.g. HATU) forming a stable amide bond. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.

Application

PEGylation of Protein, Peptide & Oligo > Amine Reactive > PEG Acid | Antibody Drug Conjugates > Amine Reactive > PEG Acid | Drug Delivery, Surface Modification > Amine Reactive > PEG Acid | Products > PEG Linkers > PEG Acid | Products > PEG Linkers > PEG Acid > Cbz-N-amido-PEG-acid

Product Information

• Catalog No.: BP-28387
• CAS No.: 1451362-51-8
• Molecular Formula: C18H27NO8
• Molecular Weight: 385.4
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source