Lipid TD5 is an ionizable cationic lipid (pKa = 7.3) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo.1 LNPs containing lipid TD5 undergo endocytosis in a serotonin (5-HT) receptor subtype 1A-dependent manner in primary mouse astrocytes.
PEGylation of Protein, Peptide & Oligo > Lipid Molecules > Ionizable Lipid | Drug Delivery, Surface Modification > Lipid Molecules > Ionizable Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid > Other ionizable lipid
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