Volanesorsen (ISIS 304801) is an antisense oligonucleotide inhibitor of apolipoprotein CIII ( apo-CIII ) mRNA that reduces triglyceride levels and improves insulin resistance. Volanesorsen is being studied in the treatment of hypertriglyceridemia, familial chylosiderosis syndrome, and type 2 diabetes.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Endocrinology | Products > Signaling Pathways > Apolipoprotein
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