YK-009 is an ionizable lipid with a pKa of 6.51. It has been utilized alongside other lipids to create lipid nanoparticles (LNPs). When SARS-CoV-2 Omicron variant mRNA is administered within YK-009-containing LNPs, it stimulates the production of IgG antibodies that specifically bind to the receptor-binding domain (RBD) of the virus.
PEGylation of Protein, Peptide & Oligo > Lipid Molecules > Ionizable Lipid | Drug Delivery, Surface Modification > Lipid Molecules > Ionizable Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid > SM-102 & Analogs
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