BAY-678

Overview

BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE) , with an IC 50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC).

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Elastase

Product Information

• Catalog No.: HY-111457A
• CAS No.: 675103-36-3
• Molecular Formula: C20H15F3N4O2
• Molecular Weight: 400.35
• Purity: 98.66%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (6.24 mM); Clear solution
• Availability: In-stock

Source

Original product source