Lipid HTO12 (solution in ethanol)

Overview

Lipid HTO12 is an ionizable lipid (pKa = 6.432) used in lipid nanoparticles (LNPs) for mRNA delivery. LNPs with HTO12 and adenine base editor mRNA targeting Pcsk9 reduce hepatic Pcsk9 levels in mice, requiring a lower lipid-to-mRNA ratio than SM-102-based LNPs.

Application

PEGylation of Protein, Peptide & Oligo > Lipid Molecules > Ionizable Lipid | Drug Delivery, Surface Modification > Lipid Molecules > Ionizable Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid > SM-102 & Analogs

Product Information

• Catalog No.: BP-42661
• CAS No.: 3047222-45-4
• Molecular Formula: C41H83NO4
• Molecular Weight: 654.1
• Storage: -20°C
• Availability: In Stock

Source

Original product source