3-(1-Oxo-6-piperazin-1-yl-isoindolin-2-yl)piperidine-2,6-dione

Overview

3-(1-Oxo-6-piperazin-1-yl-isoindolin-2-yl)piperidine-2,6-dione is a thalidomide-derived cereblon (CRBN) E3 ligase ligand featuring a piperazine-substituted isoindolinone core. This optimized building block enables PROTAC design and targeted protein degradation by recruiting the CRBN ubiquitin ligase complex, facilitating selective elimination of disease-relevant proteins in drug discovery. Reagent-grade; for laboratory research purposes only.

Application

PROTAC > PROTAC Linkers > PROTAC Linkers | Products > PROTAC, Molecular glue > PROTAC Linkers | Products > PROTAC, Molecular glue > PROTAC Linkers > Lenalidomide | Products > PROTAC, Molecular glue > PROTAC Linkers > Lenalidomide

Product Information

• Catalog No.: BP-42140
• CAS No.: 2229723-92-4
• Molecular Formula: C17H20N4O3
• Molecular Weight: 328.4
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source