ARD-1676

Overview

ARD-1676 is an orally bioavailable PROTAC designed for degrading the androgen receptor (AR). It comprises a ligand that targets AR and a cereblon ligand, facilitating the degradation process through the ubiquitin-proteasome system. This compound demonstrates effective AR degradation both in vitro and in vivo, contributing to the inhibition of tumor growth in mouse xenograft models. Reagent-grade; for laboratory research purposes only.

Application

Products > PROTAC, Molecular glue > Degraders

Product Information

• Catalog No.: BP-42186
• CAS No.: 2632305-36-1
• Molecular Formula: C44H46ClN7O5
• Molecular Weight: 788.4
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source