MS-436

Overview

MS 436 CAS:1395084-25-9 is a potent and selective BRD4 bromodomain inhibitor (Ki of the first bromodomain (BRD4(1)) = 30 - 50 nM), MS436 exhibits in a panel of water-mediated interactions Low nanomolar affinity (estimated Ki is 30-50 nM), with 10-fold selectivity for BRD4(1) over BRD4(2).

Application

Polyethylene Glycol PEG Linkers > PROTAC Linker > BET Inhibitors

Product Information

• Catalog No.: AP14251
• CAS No.: 1395084-25-9
• Molecular Formula: C18H17N5O3S
• Molecular Weight: 383.40
• Purity: ≥95%
• Availability: In Stock

Source

Original product source