IC8 is an ionizable lipid with a multi chargeable piperazine linked to two branched, tertiary amines. Immunization with SARS-CoV-2 spike glycoprotein mRNA in IC8- and manganese-containing LNPs induces IgG responses to both SARS-CoV-2 Delta and Omicron variants in mice.
PEGylation of Protein, Peptide & Oligo > Lipid Molecules > Ionizable Lipid | PEGylation of Protein, Peptide & Oligo > Lipid Molecules > Branched Lipid | Drug Delivery, Surface Modification > Lipid Molecules > Ionizable Lipid | Drug Delivery, Surface Modification > Lipid Molecules > Branched Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid > Multi chargeable lipid | Products > Lipids In Drug Delivery > Branched Lipid > Branched Lipid
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