SJF-0628

Overview

SJF-0628 is a RAF PROTAC degrader. It induces targeted degradation of BRAF in various cancer cell lines such as colorectal cancer cell lines (Colo-205, LS-411N, HT-29, RKO) and triple-negative breast cancer cell line DU-4475. SJF-0628 decreases pMEK and pErk levels in DU-4475 cells. Reagent-grade; for laboratory research purposes only.

Application

Products > PROTAC, Molecular glue > Degraders

Product Information

• Catalog No.: BP-42192
• CAS No.: 2413035-41-1
• Molecular Formula: C51H57F2N9O7S2
• Molecular Weight: 1010.2
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source