TBAJ-587

Overview

TBAJ-587, a potent anti-tuberculosis agent, inhibits M.tb strain H37Rv growth with MIC 90 s of 0.006 and <0.02 μg/mL in MABA and LORA assay, respectively. TBAJ-587 inhibits hERG channel minimally, attenuates inhibition of the cardiac potassium channel protein coded by the hERG, which is important for cardiac repolarization.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Bacterial Infection | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Mycobacterium Tuberculosis Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Cardiovascular Disease | Products > Research Areas > Infection | Products > Signaling Pathways > Bacterial

Product Information

• Catalog No.: HY-111747
• CAS No.: 2252316-16-6
• Molecular Formula: C30H33BrFN3O5
• Molecular Weight: 614.50
• Purity: 99.69%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.17 mg/mL (3.53 mM); Clear solution
• Availability: In-stock

Source

Original product source