Setidegrasib

Overview

Setidegrasib is a quinazoline-linked (4R)-4-hydroxy-L-prolinamide-based PROTAC designed to target and degrade the G12D-mutant KRAS protein. Its structure enables selective recruitment of the mutant protein for proteasomal degradation. Reagent-grade; for laboratory research purposes only.

Application

Products > PROTAC, Molecular glue > Degraders

Product Information

• Catalog No.: BP-42173
• CAS No.: 2821793-99-9
• Molecular Formula: C60H65FN12O7S
• Molecular Weight: 1117.3
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source