PROTAC CRABP-II Degrader-1 is a cellular retinoic acid-binding protein ( CRABP-II ) SNIPER degrader. PROTAC CRABP-II Degrader-1 hijacks the cIAP1 E3 ligase to induce ubiquitination and proteasomal degradation of CRABP-II . PROTAC CRABP-II Degrader-1 can be used for the research of neuroblastoma. (Pink: CRABP-II ligand ( HY-14649 ); Blue: IAP ligand ( HY-B0134 ); Black: linker).
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