Beta-NF-JQ1

Overview

β-NF-JQ1 is a PROTAC that employs Aryl Hydrocarbon Receptor (AhR) E3 ligase for targeted protein degradation. Utilizing β-NF as an AhR ligand, it specifically engages bromodomain-containing (BRD) proteins, promoting their interaction with AhR. This compound demonstrates significant efficacy in reducing BRD protein levels, which is associated with enhanced anticancer activity. Reagent-grade; for laboratory research purposes only.

Application

Products > PROTAC, Molecular glue > Degraders

Product Information

• Catalog No.: BP-42184
• CAS No.: 2380000-55-3
• Molecular Formula: C45H42ClN5O6S
• Molecular Weight: 816.4
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source