PROTAC RIPK degrader-2

Overview

PROTAC RIPK degraders -2 is a non-peptide PROTAC based on von Hippel-Lindau and targets serine-threonine kinase RIPK2 , which is highly selective to the degradation of RIPK2 . PROTAC RIPK degrader-2 acts as an activator to increase cell death and activate ion channels in cancer cells. PROTAC RIPK degrader-2 also can inhibit protein interactions, such as receptors and ligands, involved in a variety of diseases, such as cancer and diabetes. (Pink: RIP kinase ligand ( HY-43784 ); Blue: VHL ligand ( HY-125845 ); Black: linker).

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Glucose Metabolism | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > RIP kinase

Product Information

• Catalog No.: HY-111866
• CAS No.: 1801547-16-9
• Molecular Formula: C52H65N7O11S3
• Molecular Weight: 1060.31
• Purity: 99.89%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 7.5 mg/mL (7.07 mM); Clear solution
• Availability: In-stock

Source

Original product source