MC-SN38

Overview

MC-SN38 is a agent-linker conjugate composed of a potent microtubule-disrupting agent SN38 and a non-cleavable MC linker to make antibody agent conjugate (ADC). SN-38, an active metabolite of the Topoisomerase I inhibitor Irinotecan, inhibits DNA synthesis and causes frequent DNA single-strand breaks.

Application

Products > ADC Linker, ADC Payload > ADC Payload | Products > ADC Linker, ADC Payload > ADC Payload > SN 38

Product Information

• Catalog No.: BP-45148
• CAS No.: 1473403-87-0
• Molecular Formula: C32H31N3O8
• Molecular Weight: 585.6
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source