Fmoc-Gly-Gly-L-Phe-N-[(Bz-estermethoxy)methyl]Glycinamide

Overview

Fmoc-Gly-Gly-L-Phe-N-[(Cbz-estermethoxy)methyl]Glycinamide (also known as "Fmoc-Gly-Gly-Phe-Gly-NH-CH₂-O-CH₂COOH") is a Fmoc and Cbz protected protease-cleavable ADC linker featuring the GGFG (Gly-Gly-Phe-Gly) sequence. The Fmoc group can be removed under basic conditions to yield a free amine for further conjugation. The Cbz protecting group can be removed via hydrogenolysis to form a free amine.

Application

Products > ADC Linker, ADC Payload > GGFG Linkers | Products > ADC Linker, ADC Payload > Cleavable Linkers > Gly-Gly-Phe-Gly (GGFG)

Product Information

• Catalog No.: BP-29527
• CAS No.: 2264011-97-2
• Molecular Formula: C40H41N5O9
• Molecular Weight: 735.8
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source