GSK215

Overview

GSK215 represents a highly effective and specific PROTAC designed to degrade focal adhesion kinase (FAK). Engineered with a binding affinity for both the VHL E3 ligase and the FAK inhibitor VS-4718, GSK215 facilitates swift and sustained degradation of FAK, resulting in a durable impact on FAK levels and a notable disconnect between pharmacokinetics/pharmacodynamics (PK/PD). Reagent-grade; for laboratory research purposes only.

Application

Products > PROTAC, Molecular glue > Degraders

Product Information

• Catalog No.: BP-41582
• CAS No.: 2743427-26-9
• Molecular Formula: C50H59F3N10O6S
• Molecular Weight: 985.2
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source